The NASB Wide-Margin Reference Edition is based upon Cambridge's new NASB Pitt Minion Reference Edition. The layout and pagination of the Old and New Testaments are identical, but here the Bible text is enlarged and offers the additional benefit of wide margins for note-making. The Bible is printed on slightly thicker paper for enhanced durability, and (like all Cambridge Bibles) is sewn for increased longevity and also to enable the Bible to open and stay flat.

This edition features red-letter text for the words of Christ, full cross-references, an extensive concordance, extra ruled pages for notes, and fifteen maps.